What's Eating Gilbert Grape is a 1993 American coming-of-age drama film directed by Lasse Hallström and starring Johnny Depp, Juliette Lewis, Mary Steenburgen, Leonardo DiCaprio and John C. Reilly. It follows a grocery store clerk living with his dysfunctional family, including his obese mother, his mentally disabled younger brother and two sisters in the fictional rural town of Endora, Iowa.