"Touch Me I'm Sick" is a song by the American alternative rock band Mudhoney. It was recorded in April 1988 at Seattle's Reciprocal Recording studio with producer Jack Endino. "Touch Me I'm Sick" was released as Mudhoney's debut single by independent record label Sub Pop on August 1, 1988. The song's lyrics, which feature dark humor, are a sarcastic take on issues such as disease and violent sex.