The Adventures of Jimmy Neutron, Boy Genius is an American animated science fiction and adventure television series created by John A. Davis for Nickelodeon. The series was produced by DNA Productions alongside O Entertainment and Nickelodeon Animation Studio. It was the first Nickelodeon cartoon to be animated in computer-generated imagery (CGI), as well as the first television series from the channel to be based on a film. Set in the fictional town of Retroville in Texas, and serving as a sequel and spin-off to the film Jimmy Neutron: Boy Genius (2001), the series follows the adventures of the title character, Jimmy Neutron, a boy genius who is frequently accompanied by his best friends, Carl Wheezer and Sheen Estevez, with Jimmy's various inventions often going awry.