Murder, Inc. was an organized crime group active from 1929 to 1941 that acted as the enforcement arm of the National Crime Syndicate – a closely connected criminal organization that included the Italian-American Mafia, the Jewish Mob, and other criminal organizations in New York City and elsewhere. Murder, Inc. was composed of both Jewish-American and Italian-American gangsters, and members were mainly recruited from poor and working-class Jewish and Italian neighborhoods in Manhattan and Brooklyn. It was initially headed by Louis "Lepke" Buchalter and later by Albert "Mad Hatter" Anastasia.