Kirby Reed is a fictional character in the Scream film series, created by Kevin Williamson and portrayed by the late Hayden Panettiere. She first appeared in Scream 4 (2011) and returns in Scream VI (2023). The character is a target in the fourth killing spree committed by Ghostface, a mysterious, masked killer who wears a ghost mask and black cloak, to pursue her and her friends. In each film, the killer targets their victims with threatening phone calls and intimate knowledge of their target's lives before one or several of the alleged victims is revealed as a killer.