The Karmapa Tulku lineage of the Gyalwa Karmapa is the oldest among the major incarnating lineages of Tibetan Buddhism, established in 1110 CE by the 1st Karmapa, Düsum Khyenpa. Karmapa means "the one who carries out buddha-activity", or "the embodiment of all the activities of the buddhas". A total of 17 Karmapa manifestations have incarnated after their predecessors predict their own rebirths in detailed letters.