Falcon 9 is a partially reusable, two-stage-to-orbit, medium-lift launch vehicle designed and manufactured in the United States by SpaceX. The first Falcon 9 launch was on June 4, 2010, and the first Commercial Resupply mission to the International Space Station (ISS) launched on October 8, 2012. In 2020, it became the first commercial rocket to launch humans to orbit. With 678 successful flights, Falcon 9 has seen the most launches among active launch vehicles; it is noted for its reliability and high launch cadence, with two in-flight failures, one partial failure and one pre-flight destruction.