Expedition 75 is the 75th long-duration expedition to the International Space Station (ISS). The expedition began with the departure of Soyuz MS-28 on 26 July 2026 with NASA astronaut Jessica Meir taking over the ISS command and is expected to conclude with the undocking of Soyuz MS-29 on 1 April 2027. It continues the extensive scientific research conducted aboard the ISS, focusing on various fields, including biology, human physiology, physics, and materials science. The crew members also maintain and upgrade the space station systems.