The Cross Bronx Expressway is a major freeway in the New York City borough of the Bronx. It is mainly designated as part of Interstate 95 (I-95), but also includes portions of I-295 and U.S. Route 1 (US 1). The Cross Bronx begins at the eastern approach to the Alexander Hamilton Bridge over the Harlem River. While I-95 leaves at the Bruckner Interchange in Throgs Neck, following the Bruckner Expressway and New England Thruway to Connecticut, the Cross Bronx Expressway continues east, carrying I-295 to the merge with the Throgs Neck Expressway near the Throgs Neck Bridge. Though the road goes primarily northwest-to-southeast, the nominal directions of all route numbers west of the Bruckner Interchange are aligned with the northbound route number going southeast, and the southbound route number going northwest.