Afrânio de Melo Franco was a Brazilian diplomat and politician. He served as Minister of Transport and Public Works from 1918 to 1919, as Minister of Foreign Affairs from 1930 to 1933, and as Minister of Justice in 1932. During the government of Delfim Moreira, Melo Franco took on many duties due to the president's health problems, becoming informally known as the ''prime-minister of Brazil''. From 1924 to 1926, he served as ambassador of Brazil to the League of Nations in Geneva.