Liu Zan (183–255), courtesy name Zhengming, was a military general of the state of Eastern Wu during the Three Kingdoms period of China. He previously served under the warlord Sun Quan in the late Eastern Han dynasty. A brave commander, he would be crippled with a leg injury for some time before taking drastic measures to heal himself. Liu Zan would, while ill, die in battle and his family would continue to serve the dynasty until their destruction in 272.