The John B. Connally Unit is a maximum-security prison for males located in unincorporated Karnes County, Texas, United States. It is located on Farm to Market Road 632, just east of U.S. Highway 181 2 miles (3.2 km) south of the city of Kenedy, and southeast of San Antonio. The prison, with about 813 acres (329 ha) of space, is operated by the Correctional Institutions Division of the Texas Department of Criminal Justice, administered as within Region IV. The unit is named for former governor and United States treasury secretary John B. Connally, Jr.