The ISIS Neutron and Muon Source is a pulsed neutron and muon source at the Rutherford Appleton Laboratory (RAL) of the Science and Technology Facilities Council (STFC), on the Harwell Science and Innovation Campus in Oxfordshire, United Kingdom. It has been operating since 1984. It uses beams of neutrons and muons to allow the study of materials at the atomic and molecular level. It has a suite of 35 instruments, each of which is individually optimised to investigate different aspects of atomic- and molecular-level properties. The research conducted at ISIS plays an important role in addressing global challenges, answering fundamental questions, and delivering scientific and socio-economic impact.