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References
- 1 2 3 ENSG00000288512 GRCh38: Ensembl release 89: ENSG00000159403, ENSG00000288512 – Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000098470 – Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ Sim RB (1981). "The human complement system serine proteases and their proenzymes". Proteolytic Enzymes, Part C. Methods in Enzymology. Vol. 80 Pt C. pp. 26–42. doi:10.1016/s0076-6879(81)80006-7. ISBN 9780121819804. PMID 6281620.
- ↑ Leytus SP, Kurachi K, Sakariassen KS, Davie EW (August 1986). "Nucleotide sequence of the cDNA coding for human complement C1r". Biochemistry. 25 (17): 4855–63. doi:10.1021/bi00365a020. PMID 3021205.
- ↑ Müller-Eberhard HJ (1988). "Molecular organization and function of the complement system". Annual Review of Biochemistry. 57: 321–47. doi:10.1146/annurev.bi.57.070188.001541. PMID 3052276.
- ↑ "Entrez Gene: C1R complement component 1, r subcomponent".
- ↑ Thielens NM, Enrie K, Lacroix M, Jaquinod M, Hernandez JF, Esser AF, Arlaud GJ (April 1999). "The N-terminal CUB-epidermal growth factor module pair of human complement protease C1r binds Ca2+ with high affinity and mediates Ca2+-dependent interaction with C1s". The Journal of Biological Chemistry. 274 (14): 9149–59. doi:10.1074/jbc.274.14.9149. PMID 10092586.
- ↑ Thiel S, Petersen SV, Vorup-Jensen T, Matsushita M, Fujita T, Stover CM, Schwaeble WJ, Jensenius JC (July 2000). "Interaction of C1q and mannan-binding lectin (MBL) with C1r, C1s, MBL-associated serine proteases 1 and 2, and the MBL-associated protein MAp19". Journal of Immunology. 165 (2): 878–87. doi:10.4049/jimmunol.165.2.878. PMID 10878362.
Further reading
- Lee SL, Wallace SL, Barone R, Blum L, Chase PH (1979). "Familial deficiency of two subunits of the first component of complement. C1r and C1s associated with a lupus erythematosus-like disease". Arthritis and Rheumatism. 21 (8): 958–67. doi:10.1002/art.1780210813. PMID 737019.
- Ward SL, Ingham KC (January 1992). "A calcium-binding monoclonal antibody that recognizes a non-calcium-binding epitope in the short consensus repeat units (SCRs) of complement C1r". Molecular Immunology. 29 (1): 83–93. doi:10.1016/0161-5890(92)90160-Y. PMID 1370572.
- Luo C, Thielens NM, Gagnon J, Gal P, Sarvari M, Tseng Y, Tosi M, Zavodszky P, Arlaud GJ, Schumaker VN (May 1992). "Recombinant human complement subcomponent C1s lacking beta-hydroxyasparagine, sialic acid, and one of its two carbohydrate chains still reassembles with C1q and C1r to form a functional C1 complex". Biochemistry. 31 (17): 4254–62. doi:10.1021/bi00132a015. PMID 1533159.
- Busby TF, Ingham KC (May 1990). "NH2-terminal calcium-binding domain of human complement C1s- mediates the interaction of C1r- with C1q". Biochemistry. 29 (19): 4613–8. doi:10.1021/bi00471a016. PMID 2372546.
- Lyons LA, Kamboh MI, Ferrell RE (1989). "Genetic studies of low-abundance human plasma proteins. XI. Linkage analysis and population genetics of the C1S subcomponent of the first complement component". Complement and Inflammation. 6 (2): 81–7. doi:10.1159/000463078. PMID 2541966.
- Nguyen VC, Tosi M, Gross MS, Cohen-Haguenauer O, Jegou-Foubert C, de Tand MF, Meo T, Frézal J (April 1988). "Assignment of the complement serine protease genes C1r and C1s to chromosome 12 region 12p13". Human Genetics. 78 (4): 363–8. doi:10.1007/BF00291737. PMID 2834284. S2CID 30582112.
- Leytus SP, Kurachi K, Sakariassen KS, Davie EW (August 1986). "Nucleotide sequence of the cDNA coding for human complement C1r". Biochemistry. 25 (17): 4855–63. doi:10.1021/bi00365a020. PMID 3021205.
- Journet A, Tosi M (December 1986). "Cloning and sequencing of full-length cDNA encoding the precursor of human complement component C1r". The Biochemical Journal. 240 (3): 783–7. doi:10.1042/bj2400783. PMC 1147487. PMID 3030286.
- Arlaud GJ, Willis AC, Gagnon J (February 1987). "Complete amino acid sequence of the A chain of human complement-classical-pathway enzyme C1r". The Biochemical Journal. 241 (3): 711–20. doi:10.1042/bj2410711. PMC 1147622. PMID 3036070.
- Chesne S, Villiers CL, Arlaud GJ, Lacroix MB, Colomb MG (January 1982). "Fluid-phase interaction of C1 inhibitor (C1 Inh) and the subcomponents C1r and C1s of the first component of complement, C1". The Biochemical Journal. 201 (1): 61–70. doi:10.1042/bj2010061. PMC 1163609. PMID 6282262.
- Arlaud GJ, Gagnon J (April 1983). "Complete amino acid sequence of the catalytic chain of human complement subcomponent C1-r". Biochemistry. 22 (8): 1758–64. doi:10.1021/bi00277a003. PMID 6303394.
- Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
- Nöthen MM, Dewald G (January 1994). "A common amino acid polymorphism in complement component C1R". Human Molecular Genetics. 3 (1): 217. doi:10.1093/hmg/3.1.217-a. PMID 8162045.
- Gasque P, Ischenko A, Legoedec J, Mauger C, Schouft MT, Fontaine M (November 1993). "Expression of the complement classical pathway by human glioma in culture. A model for complement expression by nerve cells". The Journal of Biological Chemistry. 268 (33): 25068–74. doi:10.1016/S0021-9258(19)74572-4. PMID 8227070.
- Pelloux S, Thielens NM, Hudry-Clergeon G, Pétillot Y, Filhol O, Arlaud GJ (May 1996). "Identification of a cryptic protein kinase CK2 phosphorylation site in human complement protease Clr, and its use to probe intramolecular interaction". FEBS Letters. 386 (1): 15–20. Bibcode:1996FEBSL.386...15P. doi:10.1016/0014-5793(96)00403-6. PMID 8635594. S2CID 28372780.
- Lacroix M, Rossi V, Gaboriaud C, Chevallier S, Jaquinod M, Thielens NM, Gagnon J, Arlaud GJ (May 1997). "Structure and assembly of the catalytic region of human complement protease C1r: a three-dimensional model based on chemical cross-linking and homology modeling". Biochemistry. 36 (21): 6270–82. doi:10.1021/bi962719i. PMID 9174342.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Bersch B, Hernandez JF, Marion D, Arlaud GJ (February 1998). "Solution structure of the epidermal growth factor (EGF)-like module of human complement protease C1r, an atypical member of the EGF family". Biochemistry. 37 (5): 1204–14. doi:10.1021/bi971851v. PMID 9477945.
External links
PDB gallery |
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1apq: STRUCTURE OF THE EGF-LIKE MODULE OF HUMAN C1R, NMR, 19 STRUCTURES
1gpz: THE CRYSTAL STRUCTURE OF THE ZYMOGEN CATALYTIC DOMAIN OF COMPLEMENT PROTEASE C1R
1md7: Monomeric structure of the zymogen of complement protease C1r
1md8: Monomeric structure of the active catalytic domain of complement protease C1r
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