A.P. Bio is an American television sitcom that premiered on February 1, 2018, on NBC as a mid-season replacement. It aired on NBC for two seasons until June 13, 2019, and moved to Peacock for its subsequent seasons. Set in Toledo, Ohio, the series centers on the everyday lives of the faculty and students of the fictitious Whitlock High School, in particular reluctant AP Biology teacher Jack Griffin, who refuses to teach the subject out of fury that he was denied a prestigious professorship at Harvard University in philosophy. Instead of teaching, he either ignores his students altogether or recruits them into various schemes to help him leave or get revenge. Mike O'Brien created the series and is a recurring writer. O'Brien is also one of the executive producers alongside Seth Meyers, Lorne Michaels, Andrew Singer, and Michael Shoemaker. The show also features Lyric Lewis, Mary Sohn, Jean Villepique, Paula Pell, and Patton Oswalt.